Fitzgerald P R
J Protozool. 1976 Feb;23(1):150-4. doi: 10.1111/j.1550-7408.1976.tb05259.x.
Three polycyclic, polyether, monocarboxylic acid antibiotics produced by and extracted from a strain of Streptomyces albus and designated A204 sodium, A28695A, or A204-np, were specifically tested for activity against hepatic and incidentally against intestinal coccidia of rabbits. All were effective in preventing infections and acceptable to young rabbits when prepared in pelleted feed. Weight gain, however, was not as good as inoculated, medicated rabbits as in noninoculated, nonmedicated controls. No gross pathologic changes were detected except in the livers of inoculated, nonmedicated controls which were severely infected on greatly enlarged. Livers of medicated rabbits were uninfected and normal in appearance and size.
从一株白色链霉菌中产生并提取的三种多环、多醚、单羧酸抗生素，分别命名为A204钠、A28695A或A204-np，专门测试了它们对兔肝脏球虫以及偶然对肠道球虫的活性。当制成颗粒饲料时，所有这些抗生素在预防感染方面均有效，并且幼兔可以接受。然而，与未接种、未用药的对照组相比，用药兔的体重增加不如接种并用药的兔。除了接种但未用药的对照组兔子肝脏严重感染且肿大外，未发现明显的病理变化。用药兔的肝脏未受感染，外观和大小正常。
