Lapinsky Stephen E, Hawryluck Laura
Mount Sinai Hospital, Interdepartmental Division of Critical Care, University of Toronto, 600 University Ave, Toronto, M5G 1X5, Canada.
University Health Network, Interdepartmental Division of Critical Care, University of Toronto, 500 University Ave, Toronto, M5G 1X7, Canada.
Intensive Care Med. 2003 Jun;29(6):870-875. doi: 10.1007/s00134-003-1821-0. Epub 2003 May 9.
Severe acute respiratory syndrome (SARS) is a contagious viral illness first recognized in late 2002. It has now been documented in 26 countries worldwide, with significant outbreaks in China, Hong Kong, Singapore, and Toronto. Research into identifying the etiological agent, evaluating modes of disease transmission, and treatment options is currently ongoing.
The disease can produce a severe bilateral pneumonia, with progressive hypoxemia. Up to 20% of patients require mechanical ventilatory support, with a fatal outcome occurring in about 5% of cases.
We review the current knowledge about this disease, with particular emphasis on ICU management and infection control precautions to prevent disease transmission.
严重急性呼吸综合征(SARS)是一种2002年末首次被识别的传染性病毒性疾病。目前全球已有26个国家记录到该疾病,在中国、中国香港、新加坡和多伦多有大规模爆发。目前正在进行关于确定病原体、评估疾病传播方式和治疗方案的研究。
该疾病可导致严重的双侧肺炎,并伴有进行性低氧血症。高达20%的患者需要机械通气支持,约5%的病例会出现致命结果。
我们回顾了关于这种疾病的现有知识,特别强调了重症监护病房管理和感染控制预防措施以防止疾病传播。