Ahmad Viqar Uddin, Hussain Javid, Hussain Hidayat, Jassbi Amir Reza, Ullah Farman, Lodhi Muhammad Arif, Yasin Amsha, Choudhary Muhammad Iqbal
H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan.
Chem Pharm Bull (Tokyo). 2003 Jun;51(6):719-23. doi: 10.1248/cpb.51.719.
Three new diterpene esters with a myrsinol-type skeleton have been isolated from Euphorbia decipiens BOISS. & BUHSE. The structure elucidation of the isolated compounds was based primarily on two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bond correlation (HMBC) and nuclear Overhauser effect spectroscopy (NOESY) experiments. Compounds 1 and 3 are active against prolyl endopeptidase and compound 2 showed inhibitory activity against urease enzyme.
从拟大戟（Euphorbia decipiens BOISS. & BUHSE.）中分离出了三种具有肉豆蔻醇型骨架的新型二萜酯。所分离化合物的结构解析主要基于二维（2D）-核磁共振技术，包括相关光谱法（COSY）、异核多量子相干（HMQC）、异核多键相关（HMBC）和核Overhauser效应光谱（NOESY）实验。化合物1和3对脯氨酰内肽酶有活性，化合物2对脲酶显示出抑制活性。
