Dromigny J A, Nabeth P, Perrier Gros Claude J D
Laboratoire de Biologie Médicale, Institut Pasteur de Dakar, Dakar, Senegal.
Trop Med Int Health. 2003 Aug;8(8):740-3. doi: 10.1046/j.1365-3156.2003.01085.x.
Data on the seroepidemiology of rubella in tropical African countries are still scarce. To determine the seroprevalence in Senegal, we conducted a 6 year retrospective survey among women of child bearing age in the urban region of Dakar, Senegal. The global seroprevalence determined with a commercial enzyme immunoassay among 3471 serological results was 90.1%. The distribution of this prevalence appeared stable with no significant difference between the years of study, age groups, and the socio-economic level of the districts of residence of the patients. Compared to seroepidemiological surveys performed in other western African countries, our data suggest an important and stable circulation of the virus in the region of Dakar. The lack of data on rubella and congenital rubella syndrome (CRS) in Senegal should encourage medical authorities to establish a national rubella surveillance network in order to develop a strategy to survey and control CRS in the country.
关于热带非洲国家风疹血清流行病学的数据仍然匮乏。为了确定塞内加尔的血清阳性率，我们在塞内加尔达喀尔市区对育龄妇女进行了一项为期6年的回顾性调查。通过商业酶免疫测定法在3471份血清学检测结果中确定的总体血清阳性率为90.1%。这种阳性率的分布似乎稳定，在研究年份、年龄组以及患者居住地区的社会经济水平之间没有显著差异。与在其他西非国家进行的血清流行病学调查相比，我们的数据表明该病毒在达喀尔地区有重要且稳定的传播。塞内加尔缺乏关于风疹和先天性风疹综合征（CRS）的数据，这应促使医疗当局建立一个全国性风疹监测网络，以便制定一项在该国调查和控制CRS的策略。
