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饮酒的绝经后女性的健康问题。

Health issues in postmenopausal women who drink.

作者信息

Register Thomas C, Cline J Mark, Shively Carol A

机构信息

Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

出版信息

Alcohol Res Health. 2002;26(4):299-307.

PMID:12875041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6676683/
Abstract

Alcohol use may impact the health and well-being of postmenopausal women through the direct interaction of alcohol with organ systems when alcohol is ingested, transported through the blood, and processed for removal, and by indirect means through the modification of blood concentrations of sex hormones. Circulating hormones are known to affect risk for coronary heart disease, osteoporosis, and breast cancer, which are major causes of significant illness and death in postmenopausal women. The effects of alcohol consumption on these three diseases in postmenopausal women are reviewed, along with limitations in interpreting results of studies of alcohol's effects on postmenopausal women's health.

摘要

饮酒可能会影响绝经后女性的健康和福祉。饮酒时，酒精会与器官系统直接相互作用，经血液运输并进行代谢清除；同时，酒精还会通过改变性激素的血液浓度产生间接影响。已知循环激素会影响冠心病、骨质疏松症和乳腺癌的发病风险，而这些疾病是绝经后女性重大疾病和死亡的主要原因。本文综述了饮酒对绝经后女性这三种疾病的影响，以及在解读酒精对绝经后女性健康影响的研究结果时存在的局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/78b7b32ae55b/299-307f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/3ef50ac983e3/299-307f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/3d20f5007320/299-307f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/8c2a1eba9b62/299-307f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/47d116b2dd49/299-307f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/78b7b32ae55b/299-307f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/3ef50ac983e3/299-307f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/3d20f5007320/299-307f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/8c2a1eba9b62/299-307f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/47d116b2dd49/299-307f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9349/6676683/78b7b32ae55b/299-307f4.jpg

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本文引用的文献

1
Alcohol, Hormones, and Health in Postmenopausal Women.绝经后女性的酒精、激素与健康
Alcohol Health Res World. 1994;18(3):185-188.
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Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men.饮酒模式及所饮用酒精类型在男性冠心病中的作用。
N Engl J Med. 2003 Jan 9;348(2):109-18. doi: 10.1056/NEJMoa022095.
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Postmenopausal hormone replacement therapy: scientific review.绝经后激素替代疗法：科学综述。
2004-2011 年中国育龄妇女烟草和酒精消费率：率及社会人口学影响因素。
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Effects of chronic moderate alcohol consumption and novel environment on heart rate variability in primates (Macaca fascicularis).长期适度饮酒和新环境对灵长类动物（食蟹猴）心率变异性的影响。
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BMJ. 2006 May 27;332(7552):1244-8. doi: 10.1136/bmj.38831.503113.7C. Epub 2006 May 3.
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Nutrition and survival after the diagnosis of breast cancer: a review of the evidence.乳腺癌诊断后的营养与生存：证据综述
J Clin Oncol. 2002 Aug 1;20(15):3302-16. doi: 10.1200/JCO.2002.03.008.
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Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.健康绝经后妇女使用雌激素加孕激素的风险与益处：妇女健康倡议随机对照试验的主要结果
JAMA. 2002 Jul 17;288(3):321-33. doi: 10.1001/jama.288.3.321.
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Epidemiology and outcomes of osteoporotic fractures.骨质疏松性骨折的流行病学与转归
Lancet. 2002 May 18;359(9319):1761-7. doi: 10.1016/S0140-6736(02)08657-9.
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Moderate alcohol consumption lowers risk factors for cardiovascular disease in postmenopausal women fed a controlled diet.适量饮酒可降低食用控制饮食的绝经后女性患心血管疾病的风险因素。
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