心脏手术中止血的床旁检测
Point-of-Care Testing of Hemostasis in Cardiac Surgery.
作者信息
Prisco Domenico, Paniccia Rita
机构信息
Dipartimento di Area Critica Medico Chirurgica - Sezione di Clinica Medica Generale e Cliniche Specialistiche, Università degli Studi di Firenze, Centro Trombosi, Azienda Ospedaliera Careggi, Firenze, Italy.
出版信息
Thromb J. 2003 May 6;1(1):1. doi: 10.1186/1477-9560-1-1.
Abstract
An excessive perioperative blood loss, that requires transfusion of blood products, sometimes occurs in patients undergoing cardiopulmonary bypass for cardiac surgery. Blood loss and transfusion requirements in these patients may be reduced with a better control of heparin treatment and its reversal. Blood component administration in patients with excessive post-cardiopulmonary bypass bleeding has been empiric for a long time due to turnaround times of laboratory coagulation tests. Devices are now available for rapid, point-of-care assessment of hemostasis alterations to allow an appropriate, targeted therapy. In particular, a quick evaluation of platelet and coagulation defects with new point-of-care devices can optimize the administration of pharmacological and transfusion-based therapy in patients with excessive bleeding after cardiopulmonary bypass.
摘要
在接受心脏手术体外循环的患者中，有时会出现需要输注血液制品的围手术期失血过多的情况。通过更好地控制肝素治疗及其逆转，可以减少这些患者的失血量和输血需求。由于实验室凝血检测周转时间长，长期以来，体外循环后出血过多的患者的血液成分输注一直是凭经验进行的。现在有一些设备可用于快速、床旁评估止血改变情况，以便进行适当的靶向治疗。特别是，使用新型床旁设备快速评估血小板和凝血缺陷，可以优化对体外循环后出血过多患者的药物治疗和输血治疗。
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