Awerkiew S, Bollschweiler E, Metzger R, Schneider P M, Hölscher A H, Pfister H
Institute of Virology, University of Cologne, Germany.
Med Microbiol Immunol. 2003 Aug;192(3):137-40. doi: 10.1007/s00430-002-0128-z. Epub 2002 Aug 13.
Esophageal squamous cell carcinomas ( n=23) and adenocarcinomas ( n=14) from German patients were tested for the presence of human papillomavirus (HPV) and Epstein-Barr-Virus (EBV) DNA. No DNA for either genital HPV or epidermodysplasia verruciformis-associated HPV was detected in any tumor. In contrast, 35% of squamous cell carcinomas and 36% of adenocarcinomas were shown to contain EBV DNA by nested polymerase chain reaction.
对来自德国患者的23例食管鳞状细胞癌和14例腺癌进行了人乳头瘤病毒(HPV)和爱泼斯坦-巴尔病毒(EBV)DNA检测。在任何肿瘤中均未检测到生殖器HPV或疣状表皮发育不良相关HPV的DNA。相比之下,通过巢式聚合酶链反应显示,35%的鳞状细胞癌和36%的腺癌含有EBV DNA。