Lan Y-W, Henson D B, Kwartz A J
Department of Ophthalmology, Mackay Memorial Hospital, and Mackay Junior College of Nursing, Taiwan, ROC. School of Medicine (Ophthalmology), University of Manchester, UK.
Br J Ophthalmol. 2003 Sep;87(9):1135-41. doi: 10.1136/bjo.87.9.1135.
To establish whether the structural parameters provided by the Heidelberg retina tomograph (HRT) and the laser diagnostics glaucoma scanning system (GDx) can be used to reflect functional damage in the visual field.
62 patients with primary open angle glaucoma underwent examination with the HRT, GDx, and Humphrey field analyser. The relations between the topographic parameters, retinal nerve fibre parameters, and visual field indices were analysed by scatter plot and linear regression.
Among the topographic parameters generated by the HRT, rim area had the best correlation with visual field indices. The "number," maximum modulation, and ellipse modulation generated by the GDx also had correlations with visual field indices. The correlations were better for the sectoral parameters than the global parameters. However, great interindividual variation was found in the association.
Although relations were found between some topographic parameters, RNFL parameters, and visual field indices, great interindividual variation limits the prediction of one parameter from the other. Therefore, both structural and functional aspects should be evaluated in order to obtain full characterisation of the glaucomatous damage for clinical judgment and treatment.
确定海德堡视网膜断层扫描仪（HRT）和激光诊断青光眼扫描系统（GDx）提供的结构参数是否可用于反映视野中的功能损害。
62例原发性开角型青光眼患者接受了HRT、GDx和 Humphrey视野分析仪检查。通过散点图和线性回归分析地形参数、视网膜神经纤维参数和视野指标之间的关系。
在HRT生成的地形参数中，视盘边缘面积与视野指标的相关性最好。GDx生成的“数量”、最大调制和椭圆调制也与视野指标相关。扇形参数的相关性优于整体参数。然而，发现个体间的关联存在很大差异。
虽然在一些地形参数、视网膜神经纤维层（RNFL）参数和视野指标之间发现了相关性，但个体间的巨大差异限制了通过一个参数预测另一个参数的能力。因此，为了全面表征青光眼损害以进行临床判断和治疗，应同时评估结构和功能方面。
