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南美猴子在疟疾疫苗研发与测试中的应用——综述

South American monkeys in the development and testing of malarial vaccines--a review.

作者信息

Collins W E

机构信息

Malaria Branch, Centers for Disease Control, Atlanta, Georgia 30333.

出版信息

Mem Inst Oswaldo Cruz. 1992;87 Suppl 3:401-6. doi: 10.1590/s0074-02761992000700068.

DOI:10.1590/s0074-02761992000700068
PMID:1364203
Abstract

South American Aotus and Saimiri monkeys, which are susceptible to infection with human malarias, have been used to develop models for the testing of human malaria vaccines. Studies indicate that blood-stage and sporozoite vaccines can be tested in these monkeys using appropriate strains of parasites.

摘要

易感染人类疟疾的南美洲夜猴和松鼠猴已被用于开发检测人类疟疾疫苗的模型。研究表明，可使用合适的寄生虫菌株在这些猴子身上测试血液期疫苗和子孢子疫苗。

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