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纺锤菌素和偏端霉素对A型产气荚膜梭菌芽孢形成起始的刺激作用。

Stimulation of the onset of sporulation of Clostridium perfringens type A by netropsin and distamycin.

作者信息

Ryu S, Labbe R G

机构信息

Department of Food Science, University of Massachusetts, Amherst 01003.

出版信息

Curr Microbiol. 1992 Oct;25(4):183-7. doi: 10.1007/BF01570717.

DOI:10.1007/BF01570717
PMID:1369407
Abstract

The basic peptide antibiotics, netropsin and distamycin, previously shown to inhibit sporulation of Bacillus subtilis, stimulated low levels of sporulation of Clostridium perfringens strain NCTC 8798 at concentrations of 1.0 and 0.1 microgram/ml respectively. Most sporulating cells produced in the presence of the antibiotics were defective. These were blocked at Stage III of sporulation, and many possessed forespores exterior to the sporangium. The same antibiotics could also inhibit the caffeine-induced stimulation of sporulation of this strain.

摘要

先前已证明能抑制枯草芽孢杆菌孢子形成的基本肽类抗生素纺锤菌素和偏端霉素，分别在浓度为1.0微克/毫升和0.1微克/毫升时，刺激产气荚膜梭菌NCTC 8798菌株产生低水平的孢子形成。在抗生素存在的情况下产生的大多数产孢细胞都有缺陷。这些细胞在孢子形成的第三阶段受阻，许多细胞的前芽孢位于芽孢囊外部。同样的抗生素也能抑制咖啡因对该菌株孢子形成的刺激作用。

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Curr Microbiol. 1992 Oct;25(4):183-7. doi: 10.1007/BF01570717.
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本文引用的文献

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Stimulation of Clostridium perfringens enterotoxin formation by caffeine and theobromine.咖啡因和可可碱对产气荚膜梭菌肠毒素形成的刺激作用。
Infect Immun. 1981 Oct;34(1):50-4. doi: 10.1128/iai.34.1.50-54.1981.
2
Ultrastructure of sporulating cells of Clostridium perfringens type A grown in the presence of raffinose.
Can J Microbiol. 1980 Sep;26(9):1153-7. doi: 10.1139/m80-190.
3
Ultrastructural analysis of the effect of netropsin on sporulation of Bacillus subtilis.纺锤菌素对枯草芽孢杆菌孢子形成影响的超微结构分析
Can J Microbiol. 1980 Apr;26(4):420-6. doi: 10.1139/m80-070.
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Improved medium for sporulation of Clostridium perfringens.用于产气荚膜梭菌芽孢形成的改良培养基。
Appl Microbiol. 1968 Jan;16(1):82-9. doi: 10.1128/am.16.1.82-89.1968.
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Dependent sequences of gene expression controlling spore formation in Bacillus subtilis.控制枯草芽孢杆菌孢子形成的基因表达相关序列。
Microbiol Sci. 1987 Aug;4(8):238-44.
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Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study.贝尼尔、纺锤菌素和偏端霉素在DNA中结合位点的比较。一项足迹分析研究。
Eur J Biochem. 1987 Sep 1;167(2):281-9. doi: 10.1111/j.1432-1033.1987.tb13334.x.
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Effect of various growth conditions on spore formation and bacillomycin L production in Bacillus subtilis.
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The molecular origin of DNA-drug specificity in netropsin and distamycin.纺锤菌素和偏端霉素中DNA-药物特异性的分子起源。
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Identification of the peptides of the crystals of Bacillus thuringiensis var israelensis involved in the mosquito larvicidal activity.苏云金芽孢杆菌以色列变种晶体中与杀蚊幼虫活性相关的肽段的鉴定。
Biochem Biophys Res Commun. 1985 Oct 15;132(1):19-27. doi: 10.1016/0006-291x(85)90982-9.
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Selective inhibition of sporulation of Bacillus subtilis by netropsin.纺锤菌素对枯草芽孢杆菌孢子形成的选择性抑制作用
Biochem Biophys Res Commun. 1975 Nov 3;67(1):414-20. doi: 10.1016/0006-291x(75)90331-9.