Mayer M J, Spiegler S J, Ward B, Glucs A, Kim C B
Program in Experimental Psychology, University of California, Santa Cruz 95064.
Invest Ophthalmol Vis Sci. 1992 Oct;33(11):3136-42.
Temporal contrast sensitivity in eyes at risk for exudative age-related maculopathy (ARM) was compared to that in age-matched healthy older eyes. The test stimulus was a foveally viewed, flickering, long-wavelength 2.8 degrees diameter circle in an equiluminant (photopic) surround. Retinal illuminance and decision criterion differences were experimentally controlled. Eyes in the healthy and ARM-risk groups had 20/30 or better Snellen acuity and intraocular pressure of less than 22 mmHg. Nevertheless, the ARM-risk patients were less sensitive to flicker contrast, especially for mid-temporal frequencies. This suggests that flicker sensitivity may be useful in identifying patients at risk for exudative ARM. In addition, comparison with other research reveals a paradox: Mid-temporal frequency sensitivity losses may be attributable primarily to a "high temporal frequency" mechanism.
将有渗出性年龄相关性黄斑病变（ARM）风险的眼睛的时间对比敏感度与年龄匹配的健康老年眼睛的时间对比敏感度进行了比较。测试刺激是一个在等亮度（明视觉）背景中，中央凹注视的、闪烁的、直径2.8度的长波长圆圈。视网膜照度和决策标准差异通过实验进行了控制。健康组和有ARM风险组的眼睛Snellen视力为20/30或更好，眼压低于22 mmHg。然而，有ARM风险的患者对闪烁对比度较不敏感，尤其是在中颞频率。这表明闪烁敏感度可能有助于识别有渗出性ARM风险的患者。此外，与其他研究的比较揭示了一个悖论：中颞频率敏感度损失可能主要归因于一种“高时间频率”机制。
