Holland K T, Cunliffe W J, Roberts C D
Br J Dermatol. 1977 Jun;96(6):623-6. doi: 10.1111/j.1365-2133.1977.tb05206.x.
A quantitative study was made of the microflora of 174 acne and 68 non-acne subjects. Two groups of organisms were investigated, the anaerobic diphtheroids and members of the Micrococcaceae. The results showed high numbers of both groups of bacteria in skin bearing blackheads, papules or pustules and in non-acne adolescent skin. There were significantly lower numbers of bacteria in the pilosebaceous ducts of normal looking skin in acne areas and in pre-adolescent skin when compared with non-acne adolescent skin. It is suggested that increased numbers of bacteria alone do not predispose to acne, but that their interaction with the skin, which is a function of the localized skin environment, may be important.
对174名痤疮患者和68名非痤疮患者的微生物群落进行了定量研究。研究了两组微生物，即厌氧类白喉杆菌和微球菌科成员。结果显示，在有黑头、丘疹或脓疱的皮肤以及非痤疮青少年皮肤中，这两类细菌的数量都很高。与非痤疮青少年皮肤相比，痤疮区域外观正常皮肤的毛囊皮脂腺导管以及青春期前皮肤中的细菌数量明显较少。研究表明，仅细菌数量增加并不会导致痤疮，但其与皮肤的相互作用（这是局部皮肤环境的一种功能）可能很重要。
