Wang Thomas D, Contag Christopher H, Mandella Michael J, Chan Ning Y, Kino Gordon S
Stanford University School of Medicine, Stanford, California 94305, USA.
Opt Lett. 2003 Oct 15;28(20):1915-7. doi: 10.1364/ol.28.001915.
We present a dual-axes confocal microscope that employs postobjective scanning and low-coherence heterodyne detection to collect vertical cross-sectional images from biological tissue with high axial resolution, reduced noise from scattered light, deep tissue penetration, and a large dynamic range. This architecture can be scaled down to millimeter dimensions with microelectromechanical systems technology for performance of in vivo optical biopsy.
我们展示了一种双轴共聚焦显微镜，它采用物镜后扫描和低相干外差检测技术，以高轴向分辨率从生物组织中采集垂直横截面图像，减少散射光噪声，实现深层组织穿透，并具有大动态范围。这种架构可以利用微机电系统技术缩小到毫米尺寸，以用于体内光学活检。
