Matsumoto T, Jo Y, Mibu R, Hirahashi M, Yao T, Iida M
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.
J Clin Pathol. 2003 Dec;56(12):963-5. doi: 10.1136/jcp.56.12.963.
A male patient with a 17 year history of intractable ulcerative colitis of the entire type was treated by total proctocolectomy. Colonoscopy before surgery did not identify dysplasia. Histological examination of the resected colorectum revealed that, in addition to chronic inflammatory infiltrates, there were 21 areas of microcarcinoids located in the muscularis propria and in the superficial layer of the submucosa. Carcinoids may be more common than previously thought, and they may be a reactive phenomenon to a variety of factors in ulcerative colitis.
一名患有全结肠型顽固性溃疡性结肠炎17年的男性患者接受了全直肠结肠切除术。术前结肠镜检查未发现发育异常。对切除的结直肠进行组织学检查发现,除了慢性炎症浸润外,在固有肌层和黏膜下层浅层有21个微类癌区域。类癌可能比以前认为的更常见,并且它们可能是溃疡性结肠炎中多种因素引起的一种反应性现象。