应用全基因组表达分析来鉴定可用于监测工业发酵的分子标记。
Application of genome-wide expression analysis to identify molecular markers useful in monitoring industrial fermentations.
作者信息
Higgins Vincent J, Rogers Peter J, Dawes Ian W
机构信息
Clive and Vera Ramaciotti Centre for Gene Function Analysis, University of New South Wales, Sydney, New South Wales 2052, Australia.
出版信息
Appl Environ Microbiol. 2003 Dec;69(12):7535-40. doi: 10.1128/AEM.69.12.7535-7540.2003.
Abstract
Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae identified the YOR387c and YGL258w homologues as highly inducible in zinc-depleted conditions. Induction was specific for zinc deficiency and was dependent on Zap1p. The results indicate that these sequences may be valuable molecular markers for detecting zinc deficiency in industrial fermentations.
摘要
对酿酒酵母工业菌株进行全基因组表达分析发现，YOR387c和YGL258w同源物在锌缺乏条件下具有高度可诱导性。这种诱导对锌缺乏具有特异性，并且依赖于Zap1p。结果表明，这些序列可能是检测工业发酵中锌缺乏的有价值的分子标记。
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