van der Meer S B, Forget P P, Loffeld R J, Stobberingh E, Kuijten R H, Arends J W
Department of Paediatrics, Academic Hospital Maastricht, University of Limburg, The Netherlands.
Eur J Pediatr. 1992 Nov;151(11):799-801. doi: 10.1007/BF01957927.
As part of a large, prospective study we investigated the prevalence Helicobacter pylori serum antibodies in children with recurrent abdominal pain (RAP). All patients suffered from recurrent bouts of abdominal pain for at least 6 months and ranged in age from 6 to 12 years. H. pylori antibodies were detected using an enzyme-linked immunosorbent assay. The prevalence of H. pylori antibodies in the RAP group was compared to that of a control group which consisted predominantly of pre-operative children. None of the control group suffered or had suffered from RAP. Antibodies to H. pylori were found in 7 of 82 (8.5%) RAP patients and in 2 of 39 (5.1%) control children. The latter difference is not significant and suggests that RAP is only rarely caused in children by H. pylori infection.
作为一项大型前瞻性研究的一部分，我们调查了复发性腹痛（RAP）儿童中幽门螺杆菌血清抗体的患病率。所有患者均患有复发性腹痛至少6个月，年龄在6至12岁之间。使用酶联免疫吸附测定法检测幽门螺杆菌抗体。将RAP组中幽门螺杆菌抗体的患病率与主要由术前儿童组成的对照组进行比较。对照组中没有儿童患有或曾患过RAP。82例RAP患者中有7例（8.5%）检测到幽门螺杆菌抗体，39例对照儿童中有2例（5.1%）检测到。后一差异无统计学意义，提示儿童中由幽门螺杆菌感染引起的RAP很少见。
