Fraass Benedick A, Smathers James, Deye James
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Med Phys. 2003 Dec;30(12):3206-16. doi: 10.1118/1.1626990.
Due to the significant interest in Monte Carlo dose calculations for external beam megavoltage radiation therapy from both the research and commercial communities, a workshop was held in October 2001 to assess the status of this computational method with regard to use for clinical treatment planning. The Radiation Research Program of the National Cancer Institute, in conjunction with the Nuclear Data and Analysis Group at the Oak Ridge National Laboratory, gathered a group of experts in clinical radiation therapy treatment planning and Monte Carlo dose calculations, and examined issues involved in clinical implementation of Monte Carlo dose calculation methods in clinical radiotherapy. The workshop examined the current status of Monte Carlo algorithms, the rationale for using Monte Carlo, algorithmic concerns, clinical issues, and verification methodologies. Based on these discussions, the workshop developed recommendations for future NCI-funded research and development efforts. This paper briefly summarizes the issues presented at the workshop and the recommendations developed by the group.
由于研究界和商业界对用于体外兆伏级放射治疗的蒙特卡罗剂量计算都极为关注,2001年10月举办了一次研讨会,以评估这种计算方法在临床治疗计划中的应用现状。美国国家癌症研究所的放射研究项目与橡树岭国家实验室的核数据与分析小组合作,召集了一批临床放射治疗计划和蒙特卡罗剂量计算方面的专家,探讨了蒙特卡罗剂量计算方法在临床放射治疗中临床应用所涉及的问题。该研讨会研究了蒙特卡罗算法的现状、使用蒙特卡罗的基本原理、算法相关问题、临床问题以及验证方法。基于这些讨论,研讨会为美国国家癌症研究所未来资助的研发工作提出了建议。本文简要总结了研讨会上提出的问题以及该小组制定的建议。