Lin Hsing-Pei, Huang Yang-Yang, Wu Hsueh-Yin, Kao Jau-Tsuen
Department of Laboratory Medicine, Cathay General Hospital, Taipei, Taiwan, Republic of China.
J Clin Microbiol. 2004 Jan;42(1):366-8. doi: 10.1128/JCM.42.1.366-368.2004.
To determine whether DNA detection of high-risk human papillomavirus could represent a reliable screening technique and a useful follow-up method, we investigated the performance of the Hybrid Capture II assay in detecting high-grade cervical lesions. The test positivity at 1.86 pg/ml had a high sensitivity (94.7%) and improved specificity. It was also a suitable follow-up method for detecting the recurrence of cervical intraepithelial disease in patients.
为了确定高危型人乳头瘤病毒的DNA检测是否可作为一种可靠的筛查技术和有效的随访方法,我们研究了第二代杂交捕获法检测高级别宫颈病变的性能。检测值为1.86 pg/ml时的检测阳性率具有高灵敏度(94.7%)并提高了特异性。它也是检测患者宫颈上皮内病变复发的合适随访方法。