Deluca John, Christodoulou Christopher, Diamond Bruce J, Rosenstein Elliot D, Kramer Neil, Natelson Benjamin H
Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA.
J Int Neuropsychol Soc. 2004 Jan;10(1):101-9. doi: 10.1017/S1355617704101124.
To examine the relative influence of speed of information processing versus working memory ability, CFS participants with psychiatric comorbidity (CFS-Psych) and CFS without a psychiatric history (CFS-noPsych) were examined on tests of visual and auditory processing speed and visual and auditory working memory. Compared to healthy controls (HC) and a group of participants with rheumatoid arthritis (RA), the CFS-noPsych group displayed significantly reduced performance on tests of information processing speed, but not on tests of working memory. No significant differences were observed between the CFS-Psych group and any other group in the study. The implications of group heterogeneity on the understanding of cognitive impairment in CFS are discussed.
为了研究信息处理速度与工作记忆能力的相对影响,对患有精神疾病合并症的慢性疲劳综合征患者(CFS-Psych)和无精神病史的慢性疲劳综合征患者(CFS-noPsych)进行了视觉和听觉处理速度以及视觉和听觉工作记忆测试。与健康对照组(HC)和一组类风湿性关节炎(RA)患者相比,CFS-noPsych组在信息处理速度测试中的表现显著降低,但在工作记忆测试中没有降低。在该研究中,未观察到CFS-Psych组与其他任何组之间存在显著差异。讨论了组间异质性对理解慢性疲劳综合征认知障碍的影响。