Blaser Martin J, Atherton John C
Department of Medicine, New York University School of Medicine, and New York Harbor Veterans Affairs Medical Center, New York 10016, USA.
J Clin Invest. 2004 Feb;113(3):321-33. doi: 10.1172/JCI20925.
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.
幽门螺杆菌是一种与人类共同进化的细菌，可在人与人之间传播，并持续定植于胃部。它们的种群结构是研究本土微生物群生态学的一个模型。细菌效应物与宿主反应之间精心编排的平衡使得微生物能够持续存在，宿主保持健康，但也带来了包括消化性溃疡和胃肿瘤在内的严重疾病风险。
