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头孢曲松对艰难梭菌出现的影响。

Influence of ceftriaxone on emergence of Clostridium difficile.

作者信息

Lejko-Zupanc T, Zakelj J, Strle F, Janc M, Pleterski-Rigler D

机构信息

Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva.

出版信息

Antimicrob Agents Chemother. 1992 Dec;36(12):2850-1. doi: 10.1128/AAC.36.12.2850.

Abstract

The influence of long-term ceftriaxone administration on the emergence of Clostridium difficile was studied with 80 patients receiving ceftriaxone for 14 days. In five patients (6.3%) C. difficile was cultured. The appearance of gastrointestinal disturbances during treatment with ceftriaxone was common, but the rate of emergence of C. difficile in immunocompetent patients was not high.

摘要

对80例接受头孢曲松治疗14天的患者进行了长期使用头孢曲松对艰难梭菌出现的影响研究。5例患者(6.3%)培养出艰难梭菌。头孢曲松治疗期间出现胃肠道紊乱很常见,但免疫功能正常患者中艰难梭菌的出现率并不高。

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本文引用的文献

2
Review of Clostridium difficile-associated diseases.艰难梭菌相关疾病综述。
Am J Infect Control. 1986 Jun;14(3):99-109. doi: 10.1016/0196-6553(86)90018-0.
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Treatment of late Lyme borreliosis--randomised comparison of ceftriaxone and penicillin.
Lancet. 1988 May 28;1(8596):1191-4. doi: 10.1016/s0140-6736(88)92011-9.
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