Lejko-Zupanc T, Zakelj J, Strle F, Janc M, Pleterski-Rigler D
Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva.
Antimicrob Agents Chemother. 1992 Dec;36(12):2850-1. doi: 10.1128/AAC.36.12.2850.
The influence of long-term ceftriaxone administration on the emergence of Clostridium difficile was studied with 80 patients receiving ceftriaxone for 14 days. In five patients (6.3%) C. difficile was cultured. The appearance of gastrointestinal disturbances during treatment with ceftriaxone was common, but the rate of emergence of C. difficile in immunocompetent patients was not high.
对80例接受头孢曲松治疗14天的患者进行了长期使用头孢曲松对艰难梭菌出现的影响研究。5例患者(6.3%)培养出艰难梭菌。头孢曲松治疗期间出现胃肠道紊乱很常见,但免疫功能正常患者中艰难梭菌的出现率并不高。