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Variability of surface-exposed antigens of different strains of Moraxella catarrhalis.

作者信息

Jönsson I, Holme T, Krook A, Rahman M, Thorén M

机构信息

Department of Infectious Diseases, Huddinge Hospital, Karolinska Institute, Sweden.

出版信息

Eur J Clin Microbiol Infect Dis. 1992 Oct;11(10):919-22. doi: 10.1007/BF01962374.

DOI:10.1007/BF01962374
PMID:1486887
Abstract

For serological diagnosis of infection with Moraxella (Branhamella) catarrhalis it is important to determine if there is variability of antigenic properties among different strains. Cross-reactions of nine strains were investigated by an immunofluorescence test using sera from immunized rabbits. All titres but one were 1:256 or higher, the highest being 1:4096. Thus a high degree of antigenic similarity was demonstrated among different strains of Moraxella catarrhalis. However, the homologous titres of six sera were 2 to 16 times higher than the titres for other strains indicating strain variations in antigenic properties of some surface components. There was no correlation between lipopolysaccharide type and titre in the immunofluorescence test.

摘要

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本文引用的文献

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Preliminary serologic evidence for a pathogenic role of Branhamella catarrhalis.关于卡他布兰汉菌致病作用的初步血清学证据。
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Immunoglobulin G (IgG) serological response to Branhamella catarrhalis in patients with acute bronchopulmonary infections.急性支气管肺部感染患者对卡他布兰汉菌的免疫球蛋白G（IgG）血清学反应
J Clin Pathol. 1988 Mar;41(3):329-33. doi: 10.1136/jcp.41.3.329.
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Antigenic drift of Haemophilus influenzae in patients with chronic obstructive pulmonary disease.
Infect Immun. 1989 Oct;57(10):3038-44. doi: 10.1128/iai.57.10.3038-3044.1989.
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The surface of Branhamella catarrhalis: a systematic approach to the surface antigens of an emerging pathogen.
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Surface-exposed and antigenically conserved determinants of outer membrane proteins of Branhamella catarrhalis.卡他布兰汉菌外膜蛋白的表面暴露且抗原保守的决定簇
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An enzyme-linked immunosorbent assay for the determination of human IgG subclass antibodies directed against Branhamella catarrhalis.一种用于测定人抗卡他莫拉菌IgG亚类抗体的酶联免疫吸附测定法。
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