Miedema B W, Kelly K A
Department of Surgery, Mayo Clinic, Rochester, Minn.
Arch Surg. 1992 Mar;127(3):295-300. doi: 10.1001/archsurg.1992.01420030057011.
Ectopic pacemakers in the Roux limb are associated with delayed gastric emptying after Roux gastrectomy. The aim herein was to suppress the ectopic pacemakers by electrical pacing or to prevent them by maintaining enteric myoneural continuity with an "uncut" Roux limb, and so improve the delayed emptying. Among eight dogs with truncal vagotomy and Roux hemigastrectomy, four dogs had a pacing electrode applied to the proximal end of the Roux limb. The other four dogs had a gastrojejunostomy to an uncut Roux limb. In them, the afferent jejunal limb was occluded by staples but not divided, and a diverting jejuno-jejunostomy was performed. Roux pacing and the uncut Roux operation abolished ectopic pacemakers in the Roux limb and speeded the slow gastric emptying present in unpaced control tests. At autopsy, however, dehiscences were found in the staple line in the dogs with the uncut Roux procedures. In conclusion, electrical pacing and the uncut Roux limb show promise as techniques to prevent ectopic jejunal pacemakers and gastric stasis after Roux gastrectomy. Both must be improved before they can be used in patients.
Roux袢中的异位起搏点与Roux胃切除术后胃排空延迟有关。本文的目的是通过电起搏抑制异位起搏点,或通过“未切断”的Roux袢维持肠肌神经连续性来预防异位起搏点,从而改善延迟排空。在8只接受迷走神经干切断术和Roux半胃切除术的狗中,4只狗在Roux袢近端放置了起搏电极。另外4只狗进行了与未切断的Roux袢的胃空肠吻合术。在这些狗中,空肠传入袢用吻合钉封闭但未切断,并进行了转流性空肠-空肠吻合术。Roux起搏和未切断Roux手术消除了Roux袢中的异位起搏点,并加快了未起搏对照试验中出现的缓慢胃排空。然而,在尸检时,未切断Roux手术的狗的吻合钉线处发现了裂开。总之,电起搏和未切断的Roux袢作为预防Roux胃切除术后异位空肠起搏点和胃潴留的技术显示出前景。在用于患者之前,两者都必须改进。