Lee Jae Hyeok, Ku Chung Hwan, Baek Nam-In, Kim Sung-Hoon, Park Hee Wook, Kim Dae Keun
College of Pharmacy, Woosuk University, Samrye 565-701, Korea.
Arch Pharm Res. 2004 Jan;27(1):40-3. doi: 10.1007/BF02980043.
All ten compounds were isolated from the methanolic extract of the whole plants of Diodia teres through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as three iridoid glycosides, asperuloside, geniposidic acid and asperulosidic acid, a coumarin glycoside, scopolin, and six flavonoids, rutin, kaempferol-3-O-rutinoside, quercitrin, astragalin, isoquercitrin and quercetin by spectroscopic analysis.
所有这十种化合物都是从双花二叶葎全草的甲醇提取物中，通过反复硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱分离得到的。通过光谱分析确定它们的化学结构为三种环烯醚萜苷，即车叶草苷、栀子苷酸和车叶草苷酸，一种香豆素苷，即东莨菪苷，以及六种黄酮类化合物，即芦丁、山柰酚 - 3 - O - 芸香糖苷、槲皮苷、紫云英苷、异槲皮苷和槲皮素。
