Sedman A
Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109-0297.
Pediatr Nephrol. 1992 Jul;6(4):383-93. doi: 10.1007/BF00869743.
Aluminum intoxication is an iatrogenic disease caused by the use of aluminum compounds for phosphate binding and by the contamination of parenteral fluids. Although organ aluminum deposition was noted as early as 1880 and toxicity was documented in the 1960s, the inability to accurately measure serum and tissue aluminum prevented delineation of its toxic effects until the 1970s. Aluminum toxicity has now been conclusively shown to cause encephalopathy, metabolic bone disease, and microcytic anemia.
铝中毒是一种医源性疾病，由使用铝化合物进行磷结合以及胃肠外营养液污染所致。尽管早在1880年就已发现器官铝沉积，20世纪60年代也有关于毒性的记载，但在20世纪70年代之前，由于无法准确测量血清和组织中的铝，其毒性作用一直难以明确。现已确凿表明，铝中毒会导致脑病、代谢性骨病和小细胞性贫血。
