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人类I型和II型T细胞白血病-淋巴瘤病毒的初次分离：用于确认血清学结果不确定的献血者是否感染。

Primary isolation of human T-cell leukemia-lymphoma virus types I and II: use for confirming infection in seroindeterminate blood donors.

作者信息

Hjelle B, Mills R, Goldsmith C, Swenson S G, Cyrus S

机构信息

Department of Pathology, University of New Mexico School of Medicine, Albuquerque 87131.

出版信息

J Clin Microbiol. 1992 Aug;30(8):2195-9. doi: 10.1128/jcm.30.8.2195-2199.1992.

DOI:10.1128/jcm.30.8.2195-2199.1992
PMID:1500534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC265471/
Abstract

We describe the use of an immunofluorescence assay and coculture to confirm human T-cell leukemia-lymphoma virus (HTLV) infection. Peripheral blood mononuclear cells from 32 of 32 seropositive donors were positive in the immunofluorescence assay, and 63% of their cocultures produced p24 antigen. Specific antibodies distinguished HTLV type I (HTLV-I) from HTLV-II. HTLV-I or HTLV-II was isolated from donors with indeterminate serologic test results.

摘要

我们描述了使用免疫荧光测定法和共培养来确认人类T细胞白血病-淋巴瘤病毒（HTLV）感染的情况。32名血清反应阳性供者的外周血单个核细胞在免疫荧光测定中呈阳性，并且其共培养物中有63%产生了p24抗原。特异性抗体可区分I型HTLV（HTLV-I）和II型HTLV（HTLV-II）。从血清学检测结果不确定的供者中分离出了HTLV-I或HTLV-II。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09da/265471/d141de2f93d7/jcm00032-0301-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09da/265471/d141de2f93d7/jcm00032-0301-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09da/265471/d141de2f93d7/jcm00032-0301-a.jpg

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