Wang Wendi, Ruan Shigui
Department of Mathematics, Southwest Normal University, Chongqing 400715, PR China.
J Theor Biol. 2004 Apr 7;227(3):369-79. doi: 10.1016/j.jtbi.2003.11.014.
We propose a mathematical model to simulate the SARS outbreak in Beijing. The model consists of six subpopulations, namely susceptible, exposed, quarantined, suspect, probable and removed, as China started to report SARS cases as suspect and probable separately from April 27 and cases transferred from suspect class to probable class from May 2. By simplifying the model to a two-compartment suspect-probable model and a single-compartment probable model and using limited data, we are able to simulate the SARS outbreak in Beijing. We estimate that the reproduction number varies from 1.0698 to 3.2524 and obtain certain important epidemiological parameters.
我们提出了一个数学模型来模拟北京的非典疫情。该模型由六个亚群体组成,即易感者、暴露者、隔离者、疑似者、确诊者和康复者,因为中国从4月27日开始分别报告疑似和确诊的非典病例,并且从5月2日起病例从疑似类别转为确诊类别。通过将模型简化为两部分的疑似-确诊模型和单部分的确诊模型,并使用有限的数据,我们能够模拟北京的非典疫情。我们估计繁殖数在1.0698至3.2524之间变化,并获得了某些重要的流行病学参数。