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本文引用的文献

1
Analytical determination of homocysteine: a review.同型半胱氨酸的分析测定：综述
Talanta. 2003 Aug 29;60(6):1085-95. doi: 10.1016/S0039-9140(03)00173-5.
2
Visual detection of cysteine and homocysteine.半胱氨酸和同型半胱氨酸的视觉检测。
J Am Chem Soc. 2004 Jan 21;126(2):438-9. doi: 10.1021/ja036297t.
3
Facts and recommendations about total homocysteine determinations: an expert opinion.关于总同型半胱氨酸测定的事实与建议：专家意见
Clin Chem. 2004 Jan;50(1):3-32. doi: 10.1373/clinchem.2003.021634.
4
Postcolumn HPLC detection of mono- and oligosaccharides with a chemosensor.使用化学传感器对单糖和寡糖进行柱后高效液相色谱检测。
Org Lett. 2003 Dec 25;5(26):5007-10. doi: 10.1021/ol035978q.
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Chromophore formation in resorcinarene solutions and the visual detection of mono- and oligosaccharides.间苯二酚杯芳烃溶液中的发色团形成以及单糖和寡糖的视觉检测。
J Am Chem Soc. 2002 May 8;124(18):5000-9. doi: 10.1021/ja017713h.
6
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.血浆同型半胱氨酸作为痴呆和阿尔茨海默病的一个风险因素。
N Engl J Med. 2002 Feb 14;346(7):476-83. doi: 10.1056/NEJMoa011613.
7
Is homocysteine a pro-oxidant?同型半胱氨酸是一种促氧化剂吗？
Free Radic Res. 2001 Nov;35(5):499-505. doi: 10.1080/10715760100301511.
8
Roles of homocysteine in cell metabolism: old and new functions.同型半胱氨酸在细胞代谢中的作用：新旧功能
Eur J Biochem. 2001 Jul;268(14):3871-82. doi: 10.1046/j.1432-1327.2001.02278.x.
9
Reduction of dehydroascorbic acid by homocysteine.同型半胱氨酸对脱氢抗坏血酸的还原作用。
Biochim Biophys Acta. 2001 Feb 16;1525(1-2):173-9. doi: 10.1016/s0304-4165(00)00186-0.
10
Simple and rapid visual sensing of saccharides.糖类的简单快速视觉传感
Org Lett. 1999 Jul 29;1(2):331-4. doi: 10.1021/ol990105a.

同型半胱氨酸的直接检测

Direct detection of homocysteine.

作者信息

Wang Weihua, Escobedo Jorge O, Lawrence Candace M, Strongin Robert M

机构信息

Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.

出版信息

J Am Chem Soc. 2004 Mar 24;126(11):3400-1. doi: 10.1021/ja0318838.

DOI:10.1021/ja0318838
PMID:15025448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3376413/
Abstract

Homocysteine (Hcy) is a biomarker for significant disorders including Alzheimer's and cardiovascular disease. The monitoring of Hcy levels in plasma is of current concern. We describe highly selective colorimetric methods for the direct detection of Hcy. Inexpensive, commercially available materials are employed. The results show potential application for the detection of Hcy in human blood plasma.

摘要

同型半胱氨酸（Hcy）是包括阿尔茨海默病和心血管疾病在内的重大疾病的生物标志物。血浆中Hcy水平的监测是当前关注的问题。我们描述了用于直接检测Hcy的高选择性比色法。使用了价格低廉的市售材料。结果显示了该方法在检测人体血浆中Hcy方面的潜在应用。