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本文引用的文献

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Human immunodeficiency virus acquisition associated with genital ulcer disease and herpes simplex virus type 2 infection: a nested case-control study in Rakai, Uganda.与生殖器溃疡疾病和2型单纯疱疹病毒感染相关的人类免疫缺陷病毒感染：乌干达拉凯的一项巢式病例对照研究
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Detection of herpes simplex virus type 2-specific immunoglobulin G antibodies in African sera by using recombinant gG2, Western blotting, and gG2 inhibition.利用重组gG2、蛋白质印迹法和gG2抑制法检测非洲血清中2型单纯疱疹病毒特异性免疫球蛋白G抗体。
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Herpes simplex virus infections.单纯疱疹病毒感染
Lancet. 2001 May 12;357(9267):1513-8. doi: 10.1016/S0140-6736(00)04638-9.
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Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda.乌干达拉凯地区一夫一妻制、异性恋、一方感染HIV-1的配偶中每次性交时HIV-1传播的概率。
Lancet. 2001 Apr 14;357(9263):1149-53. doi: 10.1016/S0140-6736(00)04331-2.
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Genital herpes and public health: addressing a global problem.生殖器疱疹与公共卫生：应对全球性问题。
JAMA. 2000 Feb 9;283(6):791-4. doi: 10.1001/jama.283.6.791.
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Evaluation of an enzyme immunoassay system for measuring herpes simplex virus (HSV) type 1-specific and HSV type 2-specific IgG antibodies.一种用于检测1型单纯疱疹病毒（HSV）特异性IgG抗体和2型单纯疱疹病毒（HSV）特异性IgG抗体的酶免疫分析系统的评估。
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Typing of clinical herpes simplex virus type 1 and type 2 isolates with monoclonal antibodies.利用单克隆抗体对临床1型和2型单纯疱疹病毒分离株进行分型
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Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine.受试者工作特征（ROC）曲线：临床医学中的一种基本评估工具。
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Neonatal herpes simplex virus infections.
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Genital herpes simplex virus infections: clinical manifestations, course, and complications.生殖器单纯疱疹病毒感染：临床表现、病程及并发症
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一种用于检测乌干达人中2型单纯疱疹病毒特异性抗体的商业化、型特异性酶联免疫吸附测定的性能

Performance of a commercial, type-specific enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific antibodies in Ugandans.

作者信息

Laeyendecker Oliver, Henson Charla, Gray Ronald H, Nguyen Ruby H-N, Horne Bobbi Jo, Wawer Maria J, Serwadda David, Kiwanuka Noah, Morrow Rhoda Ashley, Hogrefe Wayne, Quinn Thomas C

机构信息

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

J Clin Microbiol. 2004 Apr;42(4):1794-6. doi: 10.1128/JCM.42.4.1794-1796.2004.

DOI:10.1128/JCM.42.4.1794-1796.2004
PMID:15071053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC387547/
Abstract

Two hundred forty-eight human immunodeficiency virus (HIV)-positive and 496 HIV-negative subjects in Uganda were tested by HerpeSelect herpes simplex virus type 2 enzyme-linked immunosorbent assay (ELISA) and Western blotting to optimize the ELISA for use in this population. A higher index cutoff value was required for optimal sensitivity and specificity, and overall performance of the assay was not affected by HIV status.

摘要

在乌干达，对248名人类免疫缺陷病毒（HIV）阳性和496名HIV阴性受试者进行了HerpeSelect 2型单纯疱疹病毒酶联免疫吸附测定（ELISA）和蛋白质印迹法检测，以优化该ELISA在这一人群中的应用。为实现最佳敏感性和特异性，需要更高的指数临界值，并且该检测的总体性能不受HIV感染状况的影响。