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三种商业免疫测定法在中国云南省商业性工作者中检测2型单纯疱疹病毒抗体的比较。

Comparison of three commercial immunoassays for detection of herpes simplex virus type 2 antibodies in commercial sex workers in Yunnan Province, China.

作者信息

Ngo Thoai D, Laeyendecker Oliver, Morrow Rhoda Ashley, Lai Shenghan, Quinn Thomas C

机构信息

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

Clin Vaccine Immunol. 2008 Aug;15(8):1301-3. doi: 10.1128/CVI.00006-08. Epub 2008 May 28.

DOI:10.1128/CVI.00006-08
PMID:18508932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2519307/
Abstract

Five hundred commercial sex workers in China were tested for herpes simplex virus type 2 by three immunoassays and Western blotting. Sensitivities for the Focus, Kalon, and Biokit assays were 86.7%, 82.3%, and 34.9%, respectively, and specificities were 91.8%, 94.2%, and 60.1%, respectively. The Focus assay performed optimally at an index of 1.5 (95.2% sensitivity and 93.4% specificity), and the Kalon assay performed optimally at an index of 1.2 (93.3% sensitivity and 95.2% specificity).

摘要

对中国500名商业性工作者采用三种免疫测定法和蛋白质印迹法检测2型单纯疱疹病毒。Focus检测法、Kalon检测法和Biokit检测法的灵敏度分别为86.7%、82.3%和34.9%,特异性分别为91.8%、94.2%和60.1%。Focus检测法在指数为1.5时表现最佳(灵敏度为95.2%,特异性为93.4%),Kalon检测法在指数为1.2时表现最佳(灵敏度为93.3%,特异性为95.2%)。

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本文引用的文献

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Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein G in a low-risk population in Hanoi, Vietnam.在越南河内的低风险人群中使用商业酶免疫测定法检测抗2型单纯疱疹病毒糖蛋白G抗体。
Clin Vaccine Immunol. 2008 Feb;15(2):382-4. doi: 10.1128/CVI.00437-06. Epub 2007 Dec 12.
2
Herpes simplex virus type 2 (HSV-2) Western blot confirmatory testing among men testing positive for HSV-2 using the focus enzyme-linked immunosorbent assay in a sexually transmitted disease clinic.在一家性传播疾病诊所,对使用斑点酶联免疫吸附测定法检测出单纯疱疹病毒2型(HSV-2)呈阳性的男性进行HSV-2免疫印迹确认检测。
Sex Transm Dis. 2005 Dec;32(12):771-7. doi: 10.1097/01.olq.0000175377.88358.f3.
3
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BMC Infect Dis. 2005 Oct 14;5:84. doi: 10.1186/1471-2334-5-84.
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