三种商业免疫测定法在中国云南省商业性工作者中检测2型单纯疱疹病毒抗体的比较。
Comparison of three commercial immunoassays for detection of herpes simplex virus type 2 antibodies in commercial sex workers in Yunnan Province, China.
作者信息
Ngo Thoai D, Laeyendecker Oliver, Morrow Rhoda Ashley, Lai Shenghan, Quinn Thomas C
机构信息
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
Clin Vaccine Immunol. 2008 Aug;15(8):1301-3. doi: 10.1128/CVI.00006-08. Epub 2008 May 28.
Abstract
Five hundred commercial sex workers in China were tested for herpes simplex virus type 2 by three immunoassays and Western blotting. Sensitivities for the Focus, Kalon, and Biokit assays were 86.7%, 82.3%, and 34.9%, respectively, and specificities were 91.8%, 94.2%, and 60.1%, respectively. The Focus assay performed optimally at an index of 1.5 (95.2% sensitivity and 93.4% specificity), and the Kalon assay performed optimally at an index of 1.2 (93.3% sensitivity and 95.2% specificity).
摘要
对中国500名商业性工作者采用三种免疫测定法和蛋白质印迹法检测2型单纯疱疹病毒。Focus检测法、Kalon检测法和Biokit检测法的灵敏度分别为86.7%、82.3%和34.9%，特异性分别为91.8%、94.2%和60.1%。Focus检测法在指数为1.5时表现最佳（灵敏度为95.2%，特异性为93.4%），Kalon检测法在指数为1.2时表现最佳（灵敏度为93.3%，特异性为95.2%）。
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