耐利福平的缓症链球菌临床分离株中的rpoB基因突变。
rpoB mutations in Streptococcus mitis clinical isolates resistant to rifampin.
作者信息
Achour Wafa, Guenni Olfa, Fines Marguerite, Leclercq Roland, Ben Hassen Assia
机构信息
Laboratoire du Centre National de Greffe de Moelle Osseuse, 1006 Tunis, Tunisia.
出版信息
Antimicrob Agents Chemother. 2004 Jul;48(7):2757-9. doi: 10.1128/AAC.48.7.2757-2759.2004.
Abstract
Activity of rifampin against 129 Streptococcus mitis isolates obtained from patients with hematologic cancer was investigated. One hundred twenty-five strains were susceptible to rifampin, and 4 were resistant (MIC = 32 to 64 microg/ml). Resistance to rifampin was related to mutations in the rpoB gene: His(526)Asn in three strains and His(526)Asp in one strain.
摘要
研究了利福平对129株从血液系统癌症患者中分离出的缓症链球菌的活性。125株菌株对利福平敏感，4株耐药（MIC = 32至64微克/毫升）。对利福平的耐药性与rpoB基因突变有关：三株菌株为His(526)Asn，一株菌株为His(526)Asp。
相似文献
1
rpoB mutations in Streptococcus mitis clinical isolates resistant to rifampin.
Antimicrob Agents Chemother. 2004 Jul;48(7):2757-9. doi: 10.1128/AAC.48.7.2757-2759.2004.
2
Rifampin resistance in Mycobacterium kansasii is associated with rpoB mutations.
Antimicrob Agents Chemother. 2001 Nov;45(11):3056-8. doi: 10.1128/AAC.45.11.3056-3058.2001.
3
In-vitro activity of rifabutin against rifampicin-resistant Mycobacterium tuberculosis isolates with known rpoB mutations.
Clin Microbiol Infect. 2004 Jul;10(7):662-5. doi: 10.1111/j.1469-0691.2004.00917.x.
4
[Characterization of rpoB mutation in rifampin - resistant clinical Mycobacterium tuberculosis isolates from China].
Zhonghua Jie He He Hu Xi Za Zhi. 2001 Apr;24(4):231-5.
5
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
Antimicrob Agents Chemother. 2005 Jun;49(6):2200-9. doi: 10.1128/AAC.49.6.2200-2209.2005.
6
[Investigation of drug-resistance to rifampin and rpoB gene sequence analysis of Mycobacterium abscessus].
Zhonghua Jie He He Hu Xi Za Zhi. 2003 Sep;26(9):544-7.
7
[Detecting rpoB gene mutation in rifampin-resistant Mycobacterium tuberculosis by using the reverse dot-blot hybridization method].
Zhonghua Jie He He Hu Xi Za Zhi. 2002 Oct;25(10):591-4.
8
Characterization of mutations in the rpoB gene associated with rifampin resistance in Rhodococcus equi isolated from foals.
J Clin Microbiol. 2001 Aug;39(8):2784-7. doi: 10.1128/JCM.39.8.2784-2787.2001.
9
High frequency of mutations in the rpoB gene in rifampin-resistant clinical isolates of Mycobacterium tuberculosis from Singapore.
J Clin Microbiol. 2005 Apr;43(4):2026-7. doi: 10.1128/JCM.43.4.2026-2027.2005.
10
Phenotypic and molecular characterization of macrolide and streptogramin resistance in Streptococcus mitis from neutropenic patients.
J Antimicrob Chemother. 2004 Jul;54(1):117-21. doi: 10.1093/jac/dkh317. Epub 2004 Jun 9.
引用本文的文献
1
Ribosome engineering of Myxococcus xanthus for enhancing the heterologous production of epothilones.
Microb Cell Fact. 2024 Dec 27;23(1):346. doi: 10.1186/s12934-024-02627-3.
2
New species genetic approach to identify strains of mitis group streptococci that are donors of rifampin resistance to Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2011 Jan;55(1):368-72. doi: 10.1128/AAC.00856-10. Epub 2010 Nov 1.
3
Activity of novel benzoxazinorifamycins against rifamycin-resistant Streptococcus pyogenes.
Antimicrob Agents Chemother. 2006 May;50(5):1908-9. doi: 10.1128/AAC.50.5.1908-1909.2006.
本文引用的文献
1
Emergence of rifampin-resistant Rhodococcus equi with several types of mutations in the rpoB gene among AIDS patients in northern Thailand.
J Clin Microbiol. 2003 Jun;41(6):2337-40. doi: 10.1128/JCM.41.6.2337-2340.2003.
2
Low-level resistance to rifampin in Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2003 Mar;47(3):863-8. doi: 10.1128/AAC.47.3.863-868.2003.
3
Rifampin resistance in Streptococcus pyogenes.
Eur J Clin Microbiol Infect Dis. 2002 May;21(5):411-3. doi: 10.1007/s10096-002-0732-2. Epub 2002 May 17.
4
rpoB mutation conferring rifampin resistance in Streptococcus pyogenes.
Antimicrob Agents Chemother. 2002 May;46(5):1571-3. doi: 10.1128/AAC.46.5.1571-1573.2002.
5
Viridans group streptococci: a reservoir of resistant bacteria in oral cavities.
Clin Microbiol Infect. 2002 Feb;8(2):65-9. doi: 10.1046/j.1198-743x.2001.00398.x.
6
Molecular analysis of rifampin resistance in Bacillus anthracis and Bacillus cereus.
Antimicrob Agents Chemother. 2002 Feb;46(2):511-3. doi: 10.1128/AAC.46.2.511-513.2002.
7
Characterization of mutations in the rpoB gene associated with rifampin resistance in Rhodococcus equi isolated from foals.
J Clin Microbiol. 2001 Aug;39(8):2784-7. doi: 10.1128/JCM.39.8.2784-2787.2001.
8
Rifampicin-resistant meningococci causing invasive disease: detection of point mutations in the rpoB gene and molecular characterization of the strains.
J Antimicrob Chemother. 2001 Feb;47(2):219-22. doi: 10.1093/jac/47.2.219.
9
Differential effect of rpoB mutations on antibacterial activities of rifampicin and KRM-1648 against Staphylococcus aureus.
J Antimicrob Chemother. 2001 Feb;47(2):153-6. doi: 10.1093/jac/47.2.153.
10
Molecular characterization of rpoB mutations conferring cross-resistance to rifamycins on methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 1999 Nov;43(11):2813-6. doi: 10.1128/AAC.43.11.2813.
Zotero 插件