Halees Anason S, Weng Zhiping
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA.
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W191-4. doi: 10.1093/nar/gkh433.
PromoSer is a web service that provides an easy and efficient approach to the batch retrieval of a large number of proximal promoters. Since its introduction last year, it has undergone continued development and expansion. At the core, there have been improvements in the filtering of the raw mRNA/EST sequences upon which all predictions are built, improvements in the alignments clustering and transcription start site prediction algorithms, and improvements in the backing database for increased performance. At the user interface level, improvements include enhanced functionality and user options, better integration with other resources on the web and a new visualization tool. PromoSer now also supports queries using a SOAP-based interface and XML-based responses. The service is publicly available at http://biowulf.bu.edu/zlab/PromoSer.
PromoSer是一项网络服务，它提供了一种简单高效的方法来批量检索大量近端启动子。自去年推出以来，它一直在持续发展和扩展。核心方面，在构建所有预测所依据的原始mRNA/EST序列的过滤、比对聚类和转录起始位点预测算法以及用于提高性能的支持数据库方面都有改进。在用户界面层面，改进包括增强的功能和用户选项、与网络上其他资源的更好整合以及一种新的可视化工具。PromoSer现在还支持使用基于SOAP的接口和基于XML的响应进行查询。该服务可在http://biowulf.bu.edu/zlab/PromoSer上公开获取。
