Minas A, Minas M, Stournara A, Tselepidis S
Veterinary Laboratory of Larissa National Reference Laboratory of Brucellosis, 6th Kilometer of National Road Larissa, Trikala, Larissa 41 110, Greece.
Prev Vet Med. 2004 Jun 10;64(1):41-7. doi: 10.1016/j.prevetmed.2004.03.007.
Vaccination of young animals (3-6-month-old sheep and goats) with Rev-1 vaccine for 15 years in Greece, importantly decreased the abortions in sheep and goats as well as the incidence of brucellosis in humans. After the stop of vaccination in 1994, all over Greece, the prevalence of brucellosis in animals and the incidence in humans quickly increased. It was a positive rank correlation (0.90) among these variables. Once an emergency mass-vaccination programme of young and adult animals with Rev-1 vaccine was started in 1998, the human incidence again decreased. The association of the vaccination coverage of animals and incidence of brucellosis in humans was not linear; the decrease in human brucellosis incidence was observed when the vaccination coverage of animals was >30%.
在希腊，对幼龄动物（3至6月龄的绵羊和山羊）使用Rev-1疫苗进行了15年的接种，显著降低了绵羊和山羊的流产率以及人类布鲁氏菌病的发病率。1994年停止接种后，在希腊全境，动物布鲁氏菌病的患病率和人类发病率迅速上升。这些变量之间存在正秩相关（0.90）。1998年启动了一项针对幼龄和成年动物的Rev-1疫苗紧急大规模接种计划后，人类发病率再次下降。动物接种覆盖率与人类布鲁氏菌病发病率之间的关联并非呈线性；当动物接种覆盖率>30%时，观察到人类布鲁氏菌病发病率下降。
