一种适用于丝虫病及其他感染的通用诊断方法。
A universally applicable diagnostic approach to filarial and other infections.
作者信息
Nutman T B, Zimmerman P A, Kubofcik J, Kostyu D D
机构信息
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
出版信息
Parasitol Today. 1994 Jun;10(6):239-43. doi: 10.1016/0169-4758(94)90127-9.
Antibody-based assays for the diagnosis of filarial and other infections cannot reliably distinguish between past and current infection, nor can they be used to assess the efficacy of chemotherapy. In this article, Thomas Nutmon, Peter Zimmerman, Joseph Kubofcik and Donna Kostyu discuss how the detection of parasite-specific PCR products using on ELISA-based assay may overcome these problems.
用于诊断丝虫及其他感染的基于抗体的检测方法，无法可靠地区分既往感染和当前感染，也不能用于评估化疗效果。在本文中，托马斯·纽特蒙、彼得·齐默尔曼、约瑟夫·库博菲克和唐娜·科斯图讨论了如何通过基于酶联免疫吸附测定（ELISA）的检测方法来检测寄生虫特异性聚合酶链反应（PCR）产物，从而克服这些问题。
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