Jones Lee W, Courneya Kerry S, Vallance Jeffrey K H, Ladha Aliya B, Mant Michael J, Belch Andrew R, Stewart Douglas A, Reiman Tony
Faculty of Physical Education, University of Alberta, E-424 Van Vliet Centre, Edmonton, Alberta, Canada.
Support Care Cancer. 2004 Nov;12(11):780-8. doi: 10.1007/s00520-004-0668-4.
The goal of this study was to examine the association between exercise and quality of life (QOL) in multiple myeloma cancer survivors.
Using a retrospective design, 156 multiple myeloma cancer survivors were mailed a questionnaire that assessed self-reported exercise behavior over three periods (prediagnosis, active treatment, and off-treatment) and QOL.
The response rate was 56% (88/ 156). Descriptive analyses indicated that 6.8% and 20.4% of survivors met national exercise guidelines during active and off-treatment periods, respectively. Exercise during active treatment and off-treatment were positively associated with overall QOL and all subdomains of QOL (all P<0.05) except physical wellbeing.
A low percentage of multiple myeloma cancer survivors are exercising regularly either during active or off-treatment periods. Survivors who report more exercise during these periods also report higher QOL. These findings suggest that a randomized controlled trial is warranted.
本研究的目的是探讨多发性骨髓瘤癌症幸存者运动与生活质量（QOL）之间的关联。
采用回顾性设计，向156名多发性骨髓瘤癌症幸存者邮寄了一份问卷，该问卷评估了三个时期（诊断前、积极治疗期和治疗后）的自我报告运动行为以及生活质量。
回复率为56%（88/156）。描述性分析表明，分别有6.8%和20.4%的幸存者在积极治疗期和治疗后期达到了国家运动指南的要求。积极治疗期和治疗后期的运动与总体生活质量以及生活质量的所有子领域均呈正相关（所有P<0.05），身体健康领域除外。
在积极治疗期或治疗后期，定期运动的多发性骨髓瘤癌症幸存者比例较低。在这些时期报告运动较多的幸存者也报告了较高的生活质量。这些发现表明有必要进行一项随机对照试验。
