Hansen Jens C, Deutch Bente, Pedersen Henning Sloth
Centre for Arctic Environmental Medicine, University of Aarhus, Vennelyst Boulevard 6, Aarhus DK-8000, Denmark.
Sci Total Environ. 2004 Sep 20;331(1-3):207-14. doi: 10.1016/j.scitotenv.2004.03.037.
In Greenland, the human intake of selenium has always been relatively high and is closely connected to intake of the traditional food of marine origin. Analyses of historic and present day human and animal hair samples have indicated that the selenium level in the marine environment has been constant over time, while the levels in humans have declined corresponding to a decrease in intake of traditional food. The Inuit population in Greenland is in dietary transition where western-style food will increasingly dominate. As a consequence, the ample supply of selenium may not be sustained in the future. We report here the selenium status in three Greenlandic population groups, Ittoqqortoormiit and Tasiilaq on the east coast and Uummannaq on the west coast. Mean whole blood concentrations ranged from 178 microg/l in Tasiilaq men to 488 microg/l in Uummannaq men. Plasma concentrations ranged from 79 microg/l in Tasiilaq women to 113 microg/l in Uummannaq men. With increasing Se concentrations in whole blood, the plasma concentrations increased but tended to stabilise a level approximately 140 microg/l. Selenium blood levels were highly significantly correlated with long chain marine fatty acids. Dietary survey and food composition data from the west coast showed that whale skin, muktuk, is the main source of Se followed by birds, seal meat and organs, and fish. Terrestrial animals contributed only insignificantly to the selenium intake. In West Greenland, daily Se intake (235 microg/day) was estimated by dietary survey; it corresponded well with a calculated intake (220 microg/day) based on the mean blood concentration.
在格陵兰岛，人类对硒的摄入量一直相对较高，且与海洋来源的传统食物摄入量密切相关。对历史和当代人类及动物毛发样本的分析表明，海洋环境中的硒水平长期以来一直保持稳定，而人类体内的硒水平则随着传统食物摄入量的减少而相应下降。格陵兰岛的因纽特人正处于饮食转变阶段，西式食物的主导地位将日益增强。因此，未来硒的充足供应可能无法持续。我们在此报告了格陵兰岛三个群体的硒状况，即东海岸的伊托考托米特和塔西拉克以及西海岸的乌马纳克。全血平均浓度范围从塔西拉克男性的178微克/升至乌马纳克男性的488微克/升。血浆浓度范围从塔西拉克女性的79微克/升至乌马纳克男性的113微克/升。随着全血中硒浓度的增加，血浆浓度也随之增加，但趋于稳定在约140微克/升的水平。硒的血液水平与长链海洋脂肪酸高度显著相关。来自西海岸的饮食调查和食物成分数据表明，鲸皮、鲸脂是硒的主要来源，其次是鸟类、海豹肉及器官和鱼类。陆生动物对硒摄入量的贡献微不足道。在西格陵兰岛，通过饮食调查估计每日硒摄入量为（235微克/天）；这与根据平均血液浓度计算得出的摄入量（220微克/天）相当吻合。
