Willke Th, Vorlop K-D
Federal Agricultural Research Centre, Institute of Technology and Biosystems Engineering, Bundesallee 50, 38116 Braunschweig, Germany.
Appl Microbiol Biotechnol. 2004 Dec;66(2):131-42. doi: 10.1007/s00253-004-1733-0. Epub 2004 Sep 15.
There are numerous possibilities for replacing chemical techniques with biotechnological methods based on renewable resources. The potential of biotechnology (products, technologies, metabolic pathways) is for the most part well known. Often the costs are still the problem. Biotechnological advances have the best chances for replacing some fine chemicals. While the raw material costs are less of a consideration here, the environmental benefit is huge, as chemical-technical processes often produce a wide range of undesirable/harmful by-products or waste. In the case of bulk chemicals (<1 US dollar/kg) the product price is affected mainly by raw material costs. As long as fossil raw materials are still relatively inexpensive, alternatives based on renewable resources cannot establish themselves. Residues and waste, which are available even at no cost in some cases, are an exception. The introduction of new technologies for the efficient use of such raw materials is currently being promoted. The utilisation of residual wood, plant parts, waste fat, and crude glycerol, for example, provides great potential. For industrial chemicals (2-4 US dollars/kg), process and recovery costs play a greater role. Here, innovative production technologies and product recovery techniques (e.g. on-line product separation) can increase competitiveness.
用基于可再生资源的生物技术方法取代化学技术有多种可能性。生物技术(产品、技术、代谢途径)的潜力在很大程度上是众所周知的。成本往往仍是个问题。生物技术进步最有可能取代一些精细化学品。虽然这里原材料成本不是主要考虑因素,但环境效益巨大,因为化学技术过程往往会产生大量不良/有害副产品或废物。对于大宗化学品(<1美元/千克),产品价格主要受原材料成本影响。只要化石原料仍然相对便宜,基于可再生资源的替代品就无法立足。在某些情况下甚至免费可得的残渣和废物是个例外。目前正在推动引入有效利用此类原料的新技术。例如,利用剩余木材、植物部分、废油脂和粗甘油具有很大潜力。对于工业化学品(2 - 4美元/千克),工艺和回收成本起着更大作用。在此,创新生产技术和产品回收技术(如在线产品分离)可提高竞争力。