Kidwell M G, Ribeiro J M
Department of Ecology and Evolutionary Biology and the Department of Entomology, respectively, University of Arizona, Tucson, AZ 8572 I , USA.
Parasitol Today. 1992 Oct;8(10):325-9. doi: 10.1016/0169-4758(92)90065-a.
A number of biological procedures are currently being considered as alternatives to insecticide-based methods for the control of insect vectors of disease. Among these are the adaptation of various genetic mechanisms to drive genes of interest, such as refractoriness to malaria in mosquitoes, into natural populations, for vector control purposes. Here, Margaret Kidwell and Jose Ribeiro develop a rationale for the possible use of transposable genetic elements, one of these potential drive mechanisms, and some of the problems being faced in seeking to determine the feasibility of such a strategy are described.
目前，一些生物学方法正被视为基于杀虫剂的疾病传播昆虫控制方法的替代方案。其中包括采用各种遗传机制，将感兴趣的基因，如蚊子对疟疾的抗性基因，导入自然种群，以达到控制病媒的目的。在此，玛格丽特·基德韦尔和若泽·里贝罗阐述了可能使用转座遗传元件（这些潜在驱动机制之一）的基本原理，并描述了在寻求确定该策略可行性时所面临的一些问题。
