Department of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, California, USA; email:
Divisions of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, California, USA.
Annu Rev Genet. 2023 Nov 27;57:361-390. doi: 10.1146/annurev-genet-031623-105059. Epub 2023 Sep 18.
Genetic biocontrol aims to suppress or modify populations of species to protect public health, agriculture, and biodiversity. Advancements in genome engineering technologies have fueled a surge in research in this field, with one gene editing technology, CRISPR, leading the charge. This review focuses on the current state of CRISPR technologies for genetic biocontrol of pests and highlights the progress and ongoing challenges of using these approaches.
遗传生物防治旨在抑制或改变物种的种群,以保护公共健康、农业和生物多样性。基因组工程技术的进步推动了该领域研究的激增,其中一种基因编辑技术 CRISPR 处于领先地位。本文综述了 CRISPR 技术在害虫遗传生物防治中的应用现状,重点介绍了这些方法的进展和当前面临的挑战。