Suto Hiroyuki, Zhang Maojun, Berg Douglas E
Department of Molecular Microbiology, Campus Box 8230, Washington University Medical School, 4940 Parkview Pl., St. Louis, MO 63110, USA.
Infect Immun. 2005 Feb;73(2):1232-4. doi: 10.1128/IAI.73.2.1232-1234.2005.
To model establishment of Helicobacter pylori infection in infants, suckling mice were inoculated with mixtures of strains that preferentially colonize different gastric regions and coexist in vivo. Characterization of H. pylori recovered 2 weeks later showed that susceptibility begins earlier for some strains than for others and that the onset of susceptibility varies among mouse lines.
为模拟婴儿幽门螺杆菌感染的建立过程,给乳鼠接种了优先定殖于不同胃区域并在体内共存的菌株混合物。对2周后回收的幽门螺杆菌进行的特性分析表明,某些菌株的易感性开始时间早于其他菌株,并且易感性的起始在不同小鼠品系中有所不同。