Yasunaka Kakuko, Abe Fumiko, Nagayama Ariaki, Okabe Hikaru, Lozada-Pérez Lucio, López-Villafranco Edith, Muñiz Elizabeth Estrada, Aguilar Abigail, Reyes-Chilpa Ricardo
Department of Microbiology and Immunology, School of Medicine, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
J Ethnopharmacol. 2005 Feb 28;97(2):293-9. doi: 10.1016/j.jep.2004.11.014. Epub 2005 Jan 12.
Thirty-two extracts from 22 Mexican medicinal plants of 15 different families were assayed to determine their antibacterial activity against Escherichia coli and Staphylococcus aureus. Seventeen plants showed antibacterial activity, while five plants showed no activity against both bacteria. All of the extracts showed higher activity against Staphylococcus aureus (methicillin-sensitive and methicillin-resistant) than against Escherichia coli, except one. Among the plants examined, Bursera simaruba (L.) Sarg. (Burseraceae), Haematoxylum brasiletto H. Karst. (Fabaceae), Calophyllum brasiliense Cambess. (Clusiaceae), and Mammea americana L. (Clusiaceae) were highly active against Staphylococcus aureus. Coumarins (mammea A/BA and mammea A/AA) and xanthones, namely jacareubin and 1,3,5,6-tetrahydroxy-2-(3,3-dimethylallyl) xanthone, were isolated as the principle compounds from the last two plants.
对来自15个不同科的22种墨西哥药用植物的32种提取物进行了检测，以确定它们对大肠杆菌和金黄色葡萄球菌的抗菌活性。17种植物显示出抗菌活性，而5种植物对这两种细菌均无活性。除一种提取物外，所有提取物对金黄色葡萄球菌（甲氧西林敏感和甲氧西林耐药）的活性均高于对大肠杆菌的活性。在所检测的植物中，裂榄（橄榄科）、巴西苏木（豆科）、巴西红厚壳（藤黄科）和美国山竹（藤黄科）对金黄色葡萄球菌具有高活性。从最后两种植物中分离出香豆素（山竹素A/BA和山竹素A/AA）和呫吨酮，即巴西红厚壳素和1,3,5,6 - 四羟基 - 2 -（3,3 - 二甲基烯丙基）呫吨酮作为主要化合物。
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