Wills Quintin F, Kerrigan Claire, Soothill James S
Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, UK.
Antimicrob Agents Chemother. 2005 Mar;49(3):1220-1. doi: 10.1128/AAC.49.3.1220-1221.2005.
In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.
在由金黄色葡萄球菌引起的兔伤口感染模型中,当将2×10⁹噬菌斑形成单位(PFU)的葡萄球菌噬菌体与金黄色葡萄球菌(8×10⁷菌落形成单位,CFU)同时注射到同一皮下部位时,可预防兔体内脓肿形成。噬菌体在组织中增殖。噬菌体可能是预防葡萄球菌感染的一种有价值的手段。