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1.94微米高功率铥光纤激光对泌尿组织的消融

High-power thulium fiber laser ablation of urinary tissues at 1.94 microm.

作者信息

Fried Nathaniel M, Murray Keith E

机构信息

Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA.

出版信息

J Endourol. 2005 Jan-Feb;19(1):25-31. doi: 10.1089/end.2005.19.25.

Abstract

PURPOSE

This paper describes the preliminary testing of a new laser, the thulium fiber laser, as a potential replacement for the holmium:YAG laser for multiple applications in urology.

MATERIALS AND METHODS

A 40 W thulium fiber laser operating at a wavelength of 1.94 microm delivered radiation in a continuous-wave or pulsed mode (10 msec) through either 300-microm- or 600-microm-core low-OH silica fibers for vaporization of canine prostate and incision of animal ureter and bladder-neck tissues.

RESULTS

The thulium fiber laser vaporized prostate tissue at a rate of 0.21+/-0.02 g/min. The thermal-coagulation zone measured 500 to 2000 microm, demonstrating the potential for hemostasis. Laser incisions were also made in bladder tissue and ureter, with coagulation zones of 400 to 600 microm.

CONCLUSIONS

The thulium fiber laser has several potential advantages over the holmium laser, including smaller size, more efficient operation, more precise incision of tissues, and operation in either the pulsed or the continuous-wave mode. However, before clinical use will be possible, development of higher-power thulium fiber lasers and shorter pulse lengths will be necessary for rapid vaporization of the prostate and more precise incision of urethral/bladder-neck strictures, respectively.

摘要

目的

本文描述了一种新型激光——铥光纤激光的初步测试情况,该激光有望替代钬激光,用于泌尿外科的多种应用。

材料与方法

一台40瓦的铥光纤激光,波长为1.94微米,通过300微米或600微米芯的低羟基石英光纤,以连续波或脉冲模式(10毫秒)发射辐射,用于汽化犬前列腺以及切开动物输尿管和膀胱颈组织。

结果

铥光纤激光汽化前列腺组织的速率为0.21±0.02克/分钟。热凝固区为500至2000微米,显示出止血潜力。还对膀胱组织和输尿管进行了激光切开,凝固区为400至600微米。

结论

铥光纤激光相对于钬激光具有若干潜在优势,包括体积更小、运行效率更高、组织切割更精确以及可在脉冲或连续波模式下运行。然而,在能够临床应用之前,分别开发更高功率的铥光纤激光和更短脉冲长度,对于快速汽化前列腺以及更精确地切开尿道/膀胱颈狭窄是必要的。

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