[上海曹家渡社区年龄相关性黄斑变性患病率研究]

[Prevalence study of age-related macular degeneration in Caojiadu blocks, Shanghai].

作者信息

Zou Hai-dong, Zhang Xi, Xu Xun, Wang Feng-hua, Zhang Shi-jie

机构信息

Department of Ophthalmology, First People's Hospital, Medical College of Shanghai Jiaotong University, Shanghai 200080, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2005 Jan;41(1):15-9.

PMID:15774107

Abstract

OBJECTIVE

To investigate the prevalence of age-related maculopathy (AMD) in Shanghai residents older than 50 years.

METHODS

1023 individuals were examined in the years 2002 and 2003 for clinical and subjective signs of dry and exudative AMD. A interview concerning clinical symptoms of AMD as also a complete eye exam was performed. Non-mydriatic retinoscopy was done by use of a direct opthalmoscopy. Fundus photography was used to confirm and document the diagnosis. The diagnosis of both forms of AMD was made according to the criteria of the Sub-society of Fundus Disease, Chinese Ophthalmological Society.

RESULTS

15.5% of the included population had AMD and 19 of them were exudative AMD. The prevalences of AMD in the age groups of 50-59, 60-69, 70-79 and more than 80 were identified as 5.7%, 13.5%, 20.2% and 23.5%, respectively (chi(2) = 27.97, P < 0.01). No statistical differences were found concerning atrophic and exudative AMD related to gender, education, daily focus time, smoking, alcohol consumption and systematic diseases. In the AMD patients, 5.1% and 36.2% of the eyes were identified as blind or with low vision. In exudative AMD patients, 23.3% and 63.3% of the eyes were identified as blind or with low vision. The visual acuity of eyes with exudative AMD was significantly lower than the visual acuity of atrophic AMD eyes. (chi(2) = 15.4, P < 0.01).

CONCLUSIONS

The prevalence of AMD is high, and increasing with aging. The AMD, especially the exudative AMD, leads to severe visual impairment.

摘要

目的

调查上海市50岁以上居民年龄相关性黄斑病变（AMD）的患病率。

方法

在2002年和2003年对1023名个体进行检查，以查找干性和渗出性AMD的临床及主观体征。进行了关于AMD临床症状的访谈以及全面的眼部检查。使用直接检眼镜进行不散瞳视网膜镜检查。通过眼底摄影来确认和记录诊断结果。两种类型AMD的诊断均依据中华医学会眼科学分会眼底病学组的标准。

结果

纳入人群中15.5%患有AMD，其中19例为渗出性AMD。50 - 59岁、60 - 69岁、70 - 79岁和80岁以上年龄组的AMD患病率分别为5.7%、13.5%、20.2%和23.5%（χ² = 27.97，P < 0.01）。在萎缩性和渗出性AMD方面，未发现与性别、教育程度、每日用眼时间、吸烟、饮酒及系统性疾病相关的统计学差异。在AMD患者中，5.1%的眼睛被判定为失明或视力低下，36.2%的眼睛存在此类情况。在渗出性AMD患者中，23.3%的眼睛被判定为失明或视力低下，63.3%的眼睛存在此类情况。渗出性AMD患者眼睛的视力显著低于萎缩性AMD患者眼睛的视力（χ² = 15.4，P < 0.01）。