Avanzini G, Girotti F, Caraceni T, Spreafico R
J Neurol Neurosurg Psychiatry. 1979 Jul;42(7):581-9. doi: 10.1136/jnnp.42.7.581.
Electro-oculographic recordings were obtained from 11 patients with Huntington's disease. Significant reduction of saccadic velocity was constantly found. In all the patients vertical saccades were much more impaired than horizontal. When present, vertical saccades showed long latency, low amplitude, low velocity, and disturbances related to blinking. Following movements were jerky, and ability to perform repeated rhythmic movements was impaired. These results are in agreement with previous observations and underline the selective defect of rapid movements as a characteristic feature of Huntington's disease. Further, they suggest a possible correlation between the difficulty in performing repeated ocular movements and the impaired execution of gestural sequences involving a succession of different fundamental movements.
对11例亨廷顿舞蹈病患者进行了眼电图记录。持续发现扫视速度显著降低。所有患者的垂直扫视比水平扫视受损更严重。垂直扫视出现时，表现为潜伏期长、幅度小、速度慢以及与眨眼相关的紊乱。跟随运动不平稳，进行重复节律性运动的能力受损。这些结果与先前的观察结果一致，并强调了快速运动的选择性缺陷是亨廷顿舞蹈病的一个特征。此外，它们表明在进行重复眼球运动时的困难与涉及一系列不同基本运动的手势序列执行受损之间可能存在关联。
