Begg Stephen, Rao Chalapati, Lopez Alan D
School of Population Health, University of Queensland, Brisbane, QLD, Australia.
Int J Epidemiol. 2005 Oct;34(5):1080-7. doi: 10.1093/ije/dyi101. Epub 2005 May 23.
Reliable information on causes of death is a fundamental component of health development strategies, yet globally only about one-third of countries have access to such information. For countries currently without adequate mortality reporting systems there are useful models other than resource-intensive population-wide medical certification. Sample-based mortality surveillance is one such approach. This paper provides methods for addressing appropriate sample size considerations in relation to mortality surveillance, with particular reference to situations in which prior information on mortality is lacking.
The feasibility of model-based approaches for predicting the expected mortality structure and cause composition is demonstrated for populations in which only limited empirical data is available. An algorithm approach is then provided to derive the minimum person-years of observation needed to generate robust estimates for the rarest cause of interest in three hypothetical populations, each representing different levels of health development.
Modelled life expectancies at birth and cause of death structures were within expected ranges based on published estimates for countries at comparable levels of health development. Total person-years of observation required in each population could be more than halved by limiting the set of age, sex, and cause groups regarded as 'of interest'.
The methods proposed are consistent with the philosophy of establishing priorities across broad clusters of causes for which the public health response implications are similar. The examples provided illustrate the options available when considering the design of mortality surveillance for population health monitoring purposes.
关于死因的可靠信息是卫生发展战略的基本组成部分,但全球仅有约三分之一的国家能够获取此类信息。对于目前没有完善死亡报告系统的国家而言,除了资源密集型的全人群医学认证之外,还有其他有用的模式。基于抽样的死亡率监测就是这样一种方法。本文提供了在死亡率监测中考虑适当样本量的方法,特别针对缺乏死亡率先验信息的情况。
对于仅有有限经验数据的人群,证明了基于模型的方法预测预期死亡率结构和死因构成的可行性。然后提供了一种算法方法,以得出在三个假设人群中对最罕见的感兴趣死因生成可靠估计所需的最低观察人年数,每个假设人群代表不同的卫生发展水平。
根据已发表的类似卫生发展水平国家的估计,模拟的出生时预期寿命和死因结构在预期范围内。通过限制视为“感兴趣”的年龄、性别和死因组,可以将每个人群所需的总观察人年数减少一半以上。
所提出的方法与在公共卫生应对影响相似的广泛死因类别中确定优先事项的理念一致。提供的示例说明了在考虑为人群健康监测目的设计死亡率监测时可用的选项。