Mbongo F, Patko T, Vidal P P, Vibert N, Tran Ba Huy P, de Waele C
Laboratoire de Neurobiologie des Réseaux Sensorimoteurs, CNRS UMR 7060, Université Paris 5 et Paris 7, UFR Biomédicale des Saints-Pères, et Service ORL, Hôpital Lariboisière, Paris, France.
Audiol Neurootol. 2005 Sep-Oct;10(5):291-302. doi: 10.1159/000086081. Epub 2005 May 30.
The postural instability of patients with vestibular loss (11 with bilateral and 101 with unilateral vestibular loss) at different times following the lesion was investigated by means of posturography and compared to healthy subjects. In addition, subjects submitted to galvanic vestibular stimulation were also studied to compare their postural performances with those of patients with complete unilateral vestibular lesion. The platform consisted of a static computerized force platform, on which a seesaw platform could be placed to test the subjects in dynamic conditions. The displacement of the center of foot pressure was measured under different conditions: subjects standing on the fixed platform, eyes open and eyes closed and subjects standing on the seesaw platform, eyes open and eyes closed. In the last condition, balance was tested in the subject's pitch plane by allowing the platform to rotate forwards and backwards only and in the patient's roll plane by allowing the platform to rotate to the left and to the right. The results showed that in static conditions, only bilateral vestibular loss patients had abnormal values compared to controls. In contrast, in dynamic eyes-closed conditions, both bilateral and unilateral patients could be differentiated from controls. Bilateral patients were unable to stand up without falling in both pitch and roll planes. Unilateral patients fell in the first week following the lesion and exhibited increased postural oscillations in both planes from the 2-week up to the 1-year postlesion stage. In addition and more importantly, they fell more often or had higher sway in the roll than in the pitch plane. Therefore, this study suggests that dynamic posturography on a seesaw platform could be a valuable tool for clinical diagnosis and quantitative analysis of imbalance in patients suffering from a unilateral vestibular loss up to 1 year after the lesion.
通过姿势描记法研究了前庭功能丧失患者（11例双侧和101例单侧前庭功能丧失）在病变后不同时间的姿势不稳情况，并与健康受试者进行了比较。此外，还对接受前庭电刺激的受试者进行了研究，以比较他们与完全性单侧前庭病变患者的姿势表现。该平台由一个静态计算机化测力平台组成，在其上可放置一个跷跷板平台以在动态条件下测试受试者。在不同条件下测量足底压力中心的位移：受试者站在固定平台上，睁眼和闭眼，以及受试者站在跷跷板平台上，睁眼和闭眼。在最后一种情况下，通过仅允许平台向前和向后旋转在受试者的俯仰平面测试平衡，以及通过允许平台向左和向右旋转在患者的侧倾平面测试平衡。结果表明，在静态条件下，与对照组相比，只有双侧前庭功能丧失患者的值异常。相比之下，在动态闭眼条件下，双侧和单侧患者均可与对照组区分开来。双侧患者在俯仰和侧倾平面均无法站立而不摔倒。单侧患者在病变后第一周摔倒，并且从病变后2周直至1年阶段在两个平面均表现出姿势摆动增加。此外，更重要的是，他们在侧倾平面比在俯仰平面摔倒更频繁或摆动更大。因此，本研究表明，在跷跷板平台上进行动态姿势描记法可能是一种有价值的工具，用于临床诊断和定量分析单侧前庭功能丧失患者在病变后长达1年的失衡情况。
