Tamaki Keiji, Jeffreys Alec J
Department of Legal Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Leg Med (Tokyo). 2005 Jul;7(4):244-50. doi: 10.1016/j.legalmed.2005.02.002.
It has been 20 years since the first development of DNA fingerprinting and the start of forensic DNA typing. Ever since, human tandem repeat DNA sequences have been the main targets for forensic DNA analysis. These repeat sequences are classified into minisatellites (or VNTRs) and microsatellites (or STRs). In this brief review, we discuss the historical and current forensic applications of such tandem repeats.
自DNA指纹识别技术首次开发以及法医DNA分型技术开始以来,已经过去了20年。从那时起,人类串联重复DNA序列一直是法医DNA分析的主要目标。这些重复序列被分为微卫星(或VNTRs)和短串联重复序列(或STRs)。在这篇简短的综述中,我们讨论了此类串联重复序列在法医领域的历史和当前应用。