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[富克斯葡萄膜炎综合征——虹膜异色并非“必要条件”]

[Fuchs uveitis syndrome--heterochromia is no "conditio sine qua non"].

作者信息

Becker M D, Zierhut M

机构信息

Interdisziplinäres Uveitiszentrum, Universität, Heidelberg.

出版信息

Ophthalmologe. 2005 Jul;102(7):733-42; quiz 743-4. doi: 10.1007/s00347-005-1237-z.

Abstract

Fuchs uveitis syndrome (FUS) is typically a unilateral, chronic, low-grade inflammation of the anterior segment which manifests in young adulthood. It is underdiagnosed because of its variable clinical spectrum. Although it can mimic various forms of anterior uveitis, it is important to make the correct diagnosis, based on clinical grounds, because both the management and prognosis differ from those of other uveitides. While its etiology remains unknown, it is possible that the disease has multiple causes that lead through different pathogenic mechanisms to the same clinical entity. Although many patients do not require treatment, it is not a benign condition, as often perceived. The high incidence of glaucoma makes it mandatory that all patients with FUS should be screened at regular intervals, even if they are not being actively treated and are relatively asymptomatic.

摘要

富克斯葡萄膜炎综合征(FUS)通常是一种发生于青年期的前段单侧、慢性、低度炎症。由于其临床谱多变,该病常被漏诊。尽管它可模仿多种形式的前葡萄膜炎,但基于临床依据做出正确诊断很重要,因为其治疗和预后与其他葡萄膜炎不同。虽然其病因尚不清楚,但该病可能有多种病因,通过不同的致病机制导致相同的临床病症。尽管许多患者不需要治疗,但它并非如人们通常认为的那样是一种良性疾病。青光眼的高发病率使得所有FUS患者都必须定期进行筛查,即使他们未接受积极治疗且相对无症状。

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