Lipski P S, Bennett M K, Kelly P J, James O F
Department of Geriatric Medicine, University of Newcastle upon Tyne.
J Clin Pathol. 1992 May;45(5):450-2. doi: 10.1136/jcp.45.5.450.
Small bowel morphometry was studied in 25 subjects under the age of 70 years and 22 over the age of 70. There was no evidence of malabsorption or malnutrition in either group. Two distal duodenal endoscopic biopsy specimens were examined morphometrically. There were no significant correlations between age and areas of duodenal surface epithelium, crypts and lamina propria, heights of villi and surface epithelium, depth of crypts, crypt to villus ratio, number of intraepithelial lymphocytes, duodenal architecture, enterocytes, brush border and Brunner glands. Contrary to previous reports there was no evidence for a significant effect of age on proximal small bowel morphometry.
对25名70岁以下和22名70岁以上的受试者进行了小肠形态学研究。两组均无吸收不良或营养不良的证据。对两份十二指肠远端内镜活检标本进行了形态学检查。年龄与十二指肠表面上皮、隐窝和固有层面积、绒毛和表面上皮高度、隐窝深度、隐窝与绒毛比率、上皮内淋巴细胞数量、十二指肠结构、肠上皮细胞、刷状缘和十二指肠腺之间均无显著相关性。与之前的报道相反，没有证据表明年龄对近端小肠形态学有显著影响。
